Blar i Nord Open Research Archive på forfatter "Sætrom, Pål"
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DNA hydroxymethylation and improved growth of Nile tilapia (Oreochromis niloticus) during domestication
Konstantinidis, Ioannis (PhD in Aquatic Biosciences;no. 36, Doctoral thesis, 2020)The worldwide demand for fish consumption is highly dependent on aquaculture production because commercial fishing reached its maximum exploitation since the 90’s. However, continued expansion of the aquaculture industry ... -
DNA hydroxymethylation differences underlie phenotypic divergence of somatic growth in Nile tilapia reared in common garden
Konstantinidis, Ioannis; Sætrom, Pål; Brieuc, Marine Servane Ono; Jakobsen, Kjetill Sigurd; Liedtke, Hannes; Pohlmann, Caroline; Tsoulia, Thomais; Fernandes, Jorge Manuel de Oliveira (Peer reviewed; Journal article, 2023)Phenotypic plasticity of metabolism and growth are essential for adaptation to new environmental conditions, such as those experienced during domestication. Epigenetic regulation plays a key role in this process but the ... -
Epigenetic mapping of the somatotropic axis in Nile tilapia reveals differential DNA hydroxymethylation marks associated with growth
Konstantinidis, Ioannis; Anastasiadi, Dafni; Sætrom, Pål; Nedoluzhko, Artem; Mjelle, Robin; Podgorniak, Tomasz; Piferrer, Francesc; Fernandes, Jorge Manuel de Oliveira (Peer reviewed; Journal article, 2021)In vertebrates, the somatotropic axis comprising the pituitary gland, liver and muscle plays a major role in myogenesis. Its output in terms of muscle growth is highly affected by nutritional and environmental cues, and ... -
Genome-wide hydroxymethylation profiles in liver of female Nile tilapia with distinct growth performance
Konstantinidis, Ioannis; Sætrom, Pål; Fernandes, Jorge Manuel de Oliveira (Peer reviewed; Journal article, 2023)The mechanisms underlying the fast genome evolution that occurs during animal domestication are poorly understood. Here, we present a genome-wide epigenetic dataset that quantifies DNA hydroxymethylation at single nucleotide ... -
Major gene expression changes and epigenetic remodelling in Nile tilapia muscle after just one generation of domestication
Konstantinidis, Ioannis; Sætrom, Pål; Mjelle, Robin; Nedoluzhko, Artem; Robledo, Diego; Fernandes, Jorge Manuel de Oliveira (Peer reviewed; Journal article, 2020)The historically recent domestication of fishes has been essential to meet the protein demands of a growing human population. Selection for traits of interest during domestication is a complex process whose epigenetic basis ...